Technically the answer is Yes. If hooked up with USB 2.0 the camera will downgrade the video signal and framerate but will continue to output video. Due to the bandwidth used to stream 1080p video, standard USB 2.0 rates of 480mb/s won't be enough for a clear stream. USB 3.0 is has a rate of 4.8gb/s which is able to accommodate the high def stream.